Mass production of DNA
In order to perform many gene therapies, it is necessary to mass produce the same genes. How do we increase the number of genes? One of the most common ways to increase them is called "plasmid".
In order to perform many gene therapies, it is necessary to mass produce the same genes. How do we increase the number of genes? One of the most common ways to increase them is called "plasmid".
Do you know what a "plasmid" is? Most of you probably don't have a clue. Plasmids are DNA found outside the cell nucleus, not only in chromosomes but also in organelles such as mitochondria, and they play a role in transforming cells during cell division. So how do we use plasmids to increase DNA? Look at the figure below.
You can see that the plasmid is like a circle, as shown in the figure. The plasmid is mainly extracted from E. coli and the gene is introduced into the DNA. The plasmid is then returned to the E. coli, and as the E. coli grows, you can see that the plasmid is increasing. Plasmid vectors can easily increase the number of target genes, making gene therapy more efficient.
Plasmids, the hidden DNA found outside the cell nucleus, have made it possible to mass produce DNA.
For the spread of gene therapy, we need not only the technology but also the mass production so that many people can receive the treatment. |
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